Karen Lederer received her BFA in Printmaking and Drawing from Washington University in St. Louis in 2008 and an MFA in Printmaking from Rhode Island School of Design in 2012. She has been an artist in residence at Robert Blackburn Printmaking Workshop, Lower East Side Printshop, and the Sharpe-Walentas Studio Program. Lederer has presented her work in solo exhibitions at Cheymore Gallery, One River School, Guilford College Art Gallery, Tennis Elbow at The Journal Gallery, Grant Wahlquist Gallery, and Field Projects. She has participated in many group exhibitions, most recently at Morgan Lehman Gallery, Deanna Evans Projects, Dinner Gallery, Cristea Roberts Gallery, and Hashimoto Contemporary.

In addition to her studio practice, Lederer also currently teaches classes and workshops at LaGuardia Community College, Anderson Ranch Arts Center, Women's Studio Workshop, Center for Contemporary Printmaking, Manhattan Graphics Center, and Robert Blackburn Printmaking Workshop. She lives and works in Brooklyn.